Major League Soccer Regular Season
| Date | Opponent | Venue | Score |
| March 6, 2016 |  D.C. United | H | W 4-1 |
| March 12, 2016 |  Colorado Rapids | A | L 0-1 |
| March 19, 2016 |  San Jose Earthquakes | H | W 3-1 |
| April 2, 2016 |  Vancouver Whitecaps | A | D 0-0 |
| April 10, 2016 |  Portland Timbers | H | D 1-1 |
| April 15, 2016 |  Houston Dynamo | A | W 4-1 |
| April 23, 2016 |  Real Salt Lake | H | W 5-2 |
| May 1, 2016 |  Sporting Kansas City | A | D 1-1 |
| May 8, 2016 |  New England Revolution | H | W 4-2 |
| May 11, 2016 |  Philadelphia Union | A | D 2-2 |
| May 22, 2016 | San Jose Earthquakes | H | D 1-1 |
| May 28, 2016 |  Montreal Impact | A | L 2-3 |
| June 2, 2016 | Sporting Kansas City | H | D 0-0 |
| June 18, 2016 |  Toronto FC | A | L 0-1 |
| June 22, 2016 | Colorado Rapids | H | D 0-0 |
| June 25, 2016 | San Jose Earthquakes | A | D 1-1 |
| July 4, 2016 | Vancouver Whitecaps | H | W 2-0 |
| July 9, 2016 |  Seattle Sounders | A | W 1-0 |
| July 15, 2016 | Houston Dynamo | H | W 1-0 |
| July 23, 2016 | Portland Timbers | A | W 2-1 |
| July 31, 2016 | Seattle Sounders | A | D 1-1 |
| August 7, 2016 |  New York Red Bulls | H | D 2-2 |
| August 13, 2016 | Colorado Rapids | H | D 1-1 |
| August 20, 2016 |  New York City FC | A | L 0-1 |
| August 24, 2016 |  Chicago Fire | A | D 2-2 |
| August 27, 2016 | Vancouver Whitecaps | H | D 0-0 |
| September 3, 2016 |  Columbus Crew | H | W 2-1 |
| September 7, 2016 | Real Salt Lake | A | D 3-3 |
| September 11, 2016 |  Orlando City | H | W 4-2 |
| September 18, 2016 | Sporting Kansas City | A | D 2-2 |
| September 25, 2016 | Seattle Sounders | H | L 2-4 |
| October 1, 2016 |  FC Dallas | A | L 0-1 |
| October 16, 2016 | Houston Dynamo | A | W 1-0 |
| October 23, 2016 | FC Dallas | H | D 0-0 |
Major League Soccer Playoffs
| Date | Opponent | Venue | Score |
| October 26, 2016 | Real Salt Lake | H | W 3-1 |
| October 30, 2016 | Colorado Rapids | H | W 1-0 |
| November 6, 2016 | Colorado Rapids | A | L 1-0 (L 1-3 P) |
U.S. Open Cup
| Date | Opponent | Venue | Score |
| June 14, 2016 |  La Máquina FC | H | W 4-1 (AET) |
| June 29, 2016 | Portland Timbers | A | W 1-0 |
| July 20, 2016 | Seattle Sounders | H | W 4-2 |
| August 10, 2016 | FC Dallas | H | L 1-2 (AET) |
Friendlies
| Date | Opponent | Venue | Score |
| January 30, 2016 |  FC Shirak | H | W 2-1 |
| February 6, 2016 | Toronto FC | H | L 2-3 |
| February 9, 2016 |  Club Tijuana | H | D 0-0 |
| February 13, 2016 | San Jose Earthquakes | A | W 1-0 |
| February 17, 2016 | Seattle Sounders | H | L 0-4 |
Galaxy History 